Spatial Patterns Associating Low Birth Weight with Environmental and Behavioral Factors

Low birth weight (LBW) is a significant public health problem in the world. It was estimated globally by the World Health Organization (WHO) that prevalence of LBW was 15% of all births. In Murung Raya district LBW cases remain high. This paper aimed to identify and discuss the relationship between environmental risk factors with LBW in Murung Raya.A spatial analysis was conducted with 150 women as the total participantswho were recruited through the incidence data in 2013-2014. The questionnaires, medical records, and geographic data were measured by Stata software, ArcGis, SatScan, and Geoda. The study results indicated there was significant correlation between health behavior and environmental variables with the strength of external neighborhood effect across LBW risk factors. More intense clustering of high values (hot spots) was found through the spatial analysis showing that most of the cases were located near the defined buffer zone. This research demonstrates that the spatial pattern analysis provided greater statistical power to detect an effect that was not apparent in the previous epidemiology studies

Modulational instability of the electron cyclotron waves in an adiabatic wave - particle interaction

Modulational instability of a circularly polarized electromagnetic wave, propagation along an external constant magnetic filed in plasma is investigated. The method is based on the derivation of a nonlinear Schrodinger equation, which contains nonlinear terms associated with trapped electrons and also relativistic electron quiver velocity. Among different mechanisms of trapping the collision-less process is considered. Since we are interested in characteristic spatial scales larger than the Debye length, the condition of quasi-neutrality is assumed. The maximum growth rate is calculated and the result shows that the trapped particles prevent the spatial localization of the electron cyclotron waves

Dust-Charge Variation Effects on Dust ion Acoustic Shock Waves in Four Component Quantum Plasma

The behavior of nonlinear quantum dust ion acoustic (QDIA) shock waves in a collisionless, unmagnetized plasma consisting of inertialess quantum electrons and positrons, classical cold ions and stationary negatively charged dust grains with dust charge variation is investigated using quantum hydrodynamic (QHD) equations. The propagation of small amplitude QDIA shock waves is governed by Burgers equation. It is shown that the dust charge variation plays an important role in the formation of such QDIA shock structures. The dependence of the shock waves amplitude and thickness on the chemical potential is investigated. The present theory is applicable to analyze the formation of nonlinear structures at quantum scales in dense astrophysical objects

The relationship between nurses' clinical competency and job stress in Ahvaz university hospital, 2013

زمینه و هدف: صلاحیت بالینی پرستاری، شایستگی کاربرد همزمان دانش، مهارت، نگرش ها و ارزش ها در مراقبت از بیمار است که به دلیل اهمیت آن اخیراً مورد توجه بیشتری قرار گرفته است. با توجه به اهمیت روز افزون موضوع صلاحیت پرستاری، شناخت عوامل مرتبط با آن و از جمله استرس شغلی ضروری به نظر می رسد؛ لذا مطالعه حاضر با هدف تعیین رابطه صلاحیت بالینی و استرس شغلی پرستاران شاغل در بیمارستان های دانشگاهی شهر اهواز در سال1392 انجام شد. روش بررسی: در این پژوهش توصیفی- تحلیلی که به صورت مقطعی در طی سال 1392 انجام شد، 80 نفر پرستار شاغل در بیمارستان های آموزشی شهر اهواز از طریق نمونه گیری تصادفی انتخاب و وارد مظالعه شدند. ابزار گردآوری داده ها شامل پرسشنامه های استرس شغلی Osipow و پرسشنامه صلاحیت بالینی Benner بود که به صورت خود ایفاء تکمیل گردیدند. میزان صلاحیت بالینی پرستاران ارزیابی و ارتباط آن با استرس شغلی تعیین شد. یافته ها: بیشتر پرستاران (3/81 درصد) دارای استرس شغلی متوسط بودند. میانگین نمره کل صلاحیت بالینی پرستاران 48/18± 15/61 بود. آزمون همبستگی پیرسون نشان داد که بین استرس شغلی و صلاحیت بالینی پرستاران در تمام حیطه های آن همبستگی منفی و معنی داری وجود دارد (01/0>P). همچنین بین میزان استرس شغلی و بکارگیری صلاحیت بالینی کل ارتباط معنی داری وجود داشت (001/0>P). نتیجه گیری: بر اساس نتایج مطالعه حاضر، افزایش استرس شغلی پرستاران با کاهش صلاحیت های بالینی آنها رابطه دارد که بایستی مورد توجه مدیران پرستاری قرار گیرد

Stationary dynamics of nonlinear electron-cyclotron waves at the presence of resonant electrons

The influence of resonant electrons in phase space on the nonlinear dynamics of electron-cyclotron waves is investigated. It is shown that in the case when the frequency of externally applied electromagnetic waves is close to that of the electron-cyclotron waves, the nonlinear coupling between the electron-cyclotron waves and the resulting longitudinal perturbations is mainly caused by the pondermotive potential of the electrons. It is shown that in the competition of refraction caused by the non-resonant electrons and the relativistic nonlinearity, the influence of resonant electrons will increase strongly. The reaction of such longitudinal waves with electrons that are in resonance with high frequency electromagnetic field changes the character of the soliton propagation in an essential manner

Screening vaccine formulations for biological activity using fresh human whole blood.

Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as monoclonal antibodies, a lack of immune response to the formulation is desired. During early formulation development, various biochemical and biophysical characteristics can be monitored in a high-throughput screening (HTS) format. However, it remains impractical and arguably unethical to screen samples in this way for immunological functionality in animal models. Furthermore, data for immunological functionality lag formulation design by months, making it cumbersome to relate back to formulations in real-time. It is also likely that animal testing may not accurately reflect the response in humans. For a more effective formulation screen, a human whole blood (hWB) approach can be used to assess immunological functionality. The functional activity relates directly to the human immune response to a complete formulation (adjuvant/antigen) and includes adjuvant response, antigen response, adjuvant-modulated antigen response, stability, and potentially safety. The following commentary discusses the hWB approach as a valuable new tool to de-risk manufacture, formulation design, and clinical progression